结论新生猪同种异基因脐血输注能诱导受者对供者产生免疫耐受。
Conclusion Allogeneic umbilical blood infusion can induce immunological tolerance in the recipients in newborn pigs.
目的:研究同种异基因移植早期局部引流淋巴结和外周血t细胞的活化情况。
AIM: To study the activation of t cells from local lymph node and peripheral blood early after allotransplantation.
目的探讨同种异基因骨髓腔内骨髓移植(IBM - BMT)对小鼠早期造血功能重建的影响。
Objective to investigate the effects of allogenic intra-bone marrow bone marrow transplantation (IBM-BMT) on re-establishing hematopoiesis in mice.
结论:局部引流淋巴结T细胞CD69的表达水平可及时反映受者T细胞对同种异基因抗原的识别情况。
CONCLUSION: To detect the expression of CD69 by T cells from draining lymph node can keep insight to the allorecognition early after transplantation.
目的探讨TJU103对小鼠同种异基因造血干细胞移植模型移植物抗宿主病(GVHD)是否起预防作用。
Objective To explore the role of TJU103 in preventing graft-versus-host disease (GVHD) after allogeneic stem cell transplantation in mice.
实验组进行主要组织相容性复合物单倍型相合的同种异基因骨髓移植,对照组进行主要组织相容性复合物完全不相合的骨髓移植。
MHC haploidentical allogeneic bone marrow transplantation was performed in the experimental group and MHC mismatched bone marrow transplantation in the control group.
自体、同胎及同种异体或同种异基因细胞均可作为组织工程骨可靠的细胞来源,单纯异种成骨细胞不能作为组织工程骨的细胞来源。
Autogenous, homogenous, allograft or allogeneic cell could be used in bone tissue engineering, whereas heterogenous cell could not be used in bone tissue engineering.
结论TJU103不仅可以显著抑制体外t淋巴细胞增殖效应,而且可显著降低小鼠同种异基因造血干细胞移植模型GVHD的发生率。
Conclusion TJU103 is capable of markedly inhibiting t cell proliferative response in vitro and can decrease GVHD incidence after allogeneic stem cell transplantation in mice.
结论TJU103不仅可以显著抑制体外t淋巴细胞增殖效应,而且可显著降低小鼠同种异基因造血干细胞移植模型GVHD的发生率。
Conclusion TJU103 is capable of markedly inhibiting t cell proliferative response in vitro and can decrease GVHD incidence after allogeneic stem cell transplantation in mice.
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