结论:碳酸钙泡腾颗粒的口服生物利用度高于碳酸钙片。
Conclusion: The bioavailability of calcium carbonate effervescent granules was higher than calcium carbonate tablet.
炔雌醇口服生物利用度低,有胃肠道副作用,日给药次数多。
This drug has low bioavailability, adverse reaction of gastrointestinal tract by oral administration, and is administered frequency.
本发明药物组合物中活性化合物的口服生物利用度之高是惊人的。
The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high.
结论:壳聚糖- CEC双层包覆胰岛素脂质体有利于改善胰岛素口服生物利用度。
CONCLUSION: The insulin-liposomes double-coated with chitosan and CEC were in favor of improving oral bioavailability of insulin.
自乳化药物传递系统可显著地提高难溶性或亲脂性药物口服生物利用度,具有广阔的发展前景。
The SEDDS can dramatically improve the bioavailability of poorly water soluble or lipophilic drugs by oral administration. SEDDS will have a good developmental potential.
讨论了影响自胃肠道吸收药物生物利用度的因素,对提高难溶性药物口服生物利用度的方法进行了综述。
Factors that affect the oral bioavailability of water insoluble drugs were discussed, and a review was given on the measures of improving the oral bioavailability of water insoluble drugs.
PTK787因其对肿瘤抑制的出色疗效、口服生物利用度高等特点而成为VEGF受体酪氨酸激酶抑制剂中的佼佼者。
PTK787 is the most promising VEGF receptor- tyrosine kinase inhibitor in pipeline because of its potency in tumor inhibition and oral bioavailability.
口服阿苯达唑脂质体有较高的生物利用度并有一定的肝脏靶向性。
Oral albendazole liposomes has shown higher bioavailability and liver targeting in comparison with tablet formulation.
开发口服型的GLP-1药物存在许多难题,尤其是需要有足够的生物利用度。
There are many challenges in developing an oral formulation of GLP-1, in particular obtaining adequate bioavailability.
本工作将SOD制成微球,以提高SOD稳定性和口服相对生物利用度,且在微球制备条件方面作了进一步研究。
In this work, SOD gelatin microspheres were made with the aim to improve its stability, oral relative bioavailability, and to study the preparation conditions of microspheres.
背景:法莫替丁作为组胺H_2受体拮抗剂,其口服吸收不完全,生物利用度约为37% - 50%。
Background: As one of the histamine H_2 receptor antagonist, the oral absorption of famotidine is not complete, its bioavailability is about 37%-50%.
吸收过程是决定口服药物生物利用度的重要因素,然而很多药物的吸收机制还不明确。
The absorption process is an important factor in determining the bioavailability of orally administered drugs. however, the absorption mechanism of many drugs is not clear.
目的研制一种生物利用度高适合餐后血糖变化模式的胰岛素口服制剂。
Objective To manufacture a high bioavailability oral insulin that fit the blood glucose change after meals.
FP的口服制剂中,大多存在溶出难和生物利用度低的问题。
Most oral dosage forms of FP had low bioavailability because FP could hardly dissolve.
目的:研究国产盐酸托烷司琼胶囊与进口注射液口服给药后的人体相对生物利用度。
OBJECTIVE To study the pharmacokinetics and relative bioavailability of tropisetron hydrochloride domestic capsule and imported injection in healthy volunteers.
低生物利用度最常见于水溶性差、吸收慢的药物的口服剂型。
Low bioavailability is most common with oral dosage forms of poorly water-soluble, slowly absorbed drugs.
但灯盏花素口服剂型吸收较差,绝对生物利用度低,而注射给药给长期治疗的病人带来许多不便和痛苦。
But the oral dosage forms of Breviscapine are poorly absorbed in body, and they have low absolute bioavailability.
在急诊科开具的很多口服抗生素均具有很好的生物利用度。
Many of the oral antibiotics prescribed in the Ed have good bioavailability.
目的:研究健康男性自愿者口服国产丙硫氧嘧啶片的人体相对生物利用度及生物等效性。
AIM: To study the pharmacokinetics and relative bioavailability of propylthiouracil tablet in Chinese healthy male volunteers.
由于其口服难吸收、生物利用度低的原因,临床只用于静脉给药。这不仅给患者带来用药的不便,而且也限制了葛根素的临床应用。
However, for the sake of its low oral absorption and bioavailability, now in clinic Puerarin is administrated only by vein injection, which is inconvenient for patients and limits its clinical use.
黄芩素纳米混悬液口服给药可显著提高生物利用度。
Baicalein nanosuspension by oral administration could significantly enhance the bioavailability in rats.
本文研究了葛根素口服自乳化制剂的绝对生物利用度。
The absolute bioavailability of puerarin with self-emulsifying drug delivery systems was researched in present work.
本文研究了葛根素口服自乳化制剂的绝对生物利用度。
The absolute bioavailability of puerarin with self-emulsifying drug delivery systems was researched in present work.
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