该病属常染色体隐性遗传，与X-染色体关联，所以，母亲是基因携带者的男性表现为发病。
The disease is autosomal-recessive and linked to the X-chromosome, so that men whose mothers are carriers of the gene manifest the disease.
一项12国联合研究表明，自闭症的发病与特定关键基因异常存在关联。
Key genetic abnormalities linked to autism have been identified in research by scientists from 12 countries.
导致乳腺癌与直肠癌的变异基因截然不同也就说明这两种癌症的发病机制有着很大的差异。
The mutated genes in breast cancers and colorectal cancers were almost completely distinct, suggesting the two cancers develop along different pathways.
他们发现，史蒂芬.奎克罹患“心肌梗塞，第二类糖尿病和其他几种癌症的基因发病风险在上升”，最后使得奎克决定服用预防这类疾病的抑制素药物。
They found he had an “increased genetic risk for myocardial infarction, type 2 diabetes, and some cancers, ” and Quake decided to take a prophylactic statin as a result.
拥有单组该基因(仅当同时从母亲和父亲身上继承了等位基因时才发病)使人能够抵御疟疾。
Having one set of the genes (only inheriting allele from both mother and father causes the disease) protects against malaria.
例如，有些基因与高血压与糖尿病的低发病率有关，而另一个基因则能降低老年痴呆症的发病风险。
For example, some profiles were associated with lower rates of hypertension and diabetes, while another was linked to a reduced risk of dementia.
科学家还发现了可能会提高某些重大疾病发病率的基因。
And scientists have identified genes that might increase the risk of developing a major disease later in life.
“百岁基因”提升了有益胆固醇的含量标准，降低了心脏病的发病几率，看起来也能降低痴呆的威胁。
The 'centenarian' version raises levels of 'good' cholesterol, cutting the risk of heart disease and, it appears, dementia.
虽然目前所知道的是它们都受到基因和环境危险因素的影响，但是乳糜泻和克罗恩病的发病机理只是了解了一部分。
The pathogenesis of both celiac disease and Crohn's disease is only partly understood, although it is known that they are affected by both genetic and environmental risk factors.
鲁普斯基的三个姊妹都发生有这种变异，而他的另外四位健康的姊妹及其父母(他们都未发病)仅仅是携带变异基因。
Lupski's three sick siblings also had both of these mutations, whereas his four healthy siblings and parents (who do not have the disease) carried only one mutated gene.
而一个基因的多态性与疾病易感性及疾病表型都存在关联，是该基因直接参与发病的佐证。
A gene polymorphism and susceptibility to disease and disease phenotype correlation there is the gene directly involved in the pathogenesis of corroboration.
他选择了不要知道他是否携带e4，此基因型能大大提高早老性痴呆的发病几率。
He opted not to know whether he was carrying the epsilon 4 version, which can vastly increase the odds of developing Alzheimer's disease.
结论该结果为进一步揭示白癜风的易感基因及免疫遗传发病机制提供了线索。
Conclusions These results may provide clues to reveal the susceptibility gene of vitiligo in China and as well as the immunogenetic mechanisms of the disease.
孤独症的发病原因尚未知，但几种基因会起到作用。
The cause of autism is not known, but several genes may play a part.
最近的研究表明对于许多疾病来说，普通的基因变异仅仅能解释一小部分个体发病的风险。
Recent studies have shown that for many diseases, common genetic variants can only explain a small fraction of an individual's risk of developing the condition.
据《自然遗传学》报道，研究人员宣称2号染色体和16号染色体发生基因变异会增加雌激素受体阳性的乳腺癌发病率。
Reporting in Nature Genetics, researchers said genetic variants on chromosome 2 and on chromosome 16 May increase the risk of estrogen-receptor-positive breast cancer.
正如牛皮癣，基因，免疫系统和环境因素都认为发挥在发病的作用。
As with psoriasis genes the immune system and environmental factors are all believed to play a role in the onset of the disease.
这些来自帕金森遗传病研究所的研究表明，基因可能影响得帕金森病的敏感性和发病年龄。
These findings from the Genetic Epidemiology of Parkinson's Disease study suggest that the gene may impact susceptibility for Parkinson's disease and modify age at onset, the researchers said.
从前的研究发现有其他种类的基因同躁郁症的发病有关。
Previous studies have suggested that other genes are involved in manic-depression.
IHA为主要类型，发病与异常的促醛固酮分泌因子的增加及基因变异有关。
The etiology of IHA, the main subtype, is related with increased abnormal aldosterone excreted factor and genovariation.
携带变异基因的双拷贝会使发病风险翻一番，接近100%。
Carrying two copies of the variant gene increased the risk two-fold, to nearly 100 per cent.
新近对2型糖尿病相关多基因因素识别能力的增加，以及我们对糖尿病发病机理认识的提高，为潜在的个体化治疗提供了可能。
The recent increase in identified polygenic factors related to type 2 diabetes and our understanding of the pathogenesis of diabetes provide potential opportunities to individualize therapy.
每个带有该基因的人发病概率各不同，我的医生估计，我患上乳腺癌的几率大约是87%，卵巢癌的几率是50%。
My doctors estimated that I had an 87 percent risk of breast cancer and a 50 percent risk of ovarian cancer, although the risk is different in the case of each woman.
结论P16基因缺失在NHL发病中起一定作用，其发生率与组织亚型和治疗效果有关。
Conclusion the mutation of P16 gene may be related with the occurrence, tissue subtype and effectiveness in NHL.
结论P16基因缺失在NHL发病中起一定作用，其发生率与组织亚型和治疗效果有关。
Conclusion the mutation of P16 gene may be related with the occurrence, tissue subtype and effectiveness in NHL.
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