颗粒细胞凋亡相关蛋白通过参与凋亡通路及凋亡信号转导调节凋亡。
Apoptosis-associated proteins regulate apoptosis through taking part in the apoptosis pathway and the signal transduction in apoptosis.
目的：研究蛴螬提取物对MCF - 7人乳腺癌细胞株凋亡通路的影响，为天然药物蛴螬的开发提供实验和理论依据。
AIM: to investigate the apoptotic pathway of MCF-7 breast cancer induced by the grub extract in vitro.
结论—我们的研究发现了一条新的心脏凋亡通路，其中钙神经素使ARC发生去磷酸化反应诱导凋亡的发生。这条通路可能成为心脏凋亡机制中的组成部分。
Conclusions - Our study identifies a novel cardiac apoptotic pathway in which ARC is dephosphorylated by calcineurin. This pathway could be a component in the cardiac apoptotic machinery.
结论：PC对脑缺血再灌注损伤大鼠具有保护作用，其机制可能与其增加GRP78表达、拮抗chop表达、阻断内质网应激(ERS)启动的凋亡通路有关。
Conclusion: PC has a protective effect on cerebral IR injury, which may related to increased GRP78 and decreased CHOP expression, and to inhibition of the ERS-induced apoptosis pathway.
现对尼古丁调控细胞凋亡相关的各种信号通路及其分子机制进行综述。
This paper mainly reviews the signal pathways and molecular mechanisms of nicotine in apoptotic regulation.
本文主要评述细胞凋亡的一般通路以及胎盘发生过程中细胞凋亡的调控。
In this review, the common pathway of apoptosis and the regulation in the placenta are described.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
目的：探讨白色念珠菌诱导小鼠胸腺细胞凋亡的通路。
Objective: to investigate the pathway of C. albicans-induced murine thymocyte apoptosis.
进一步阐明心肌细胞凋亡的信号通路，将为CHF的预防和治疗提供新的途径。
Further elucidation of the signal pathway leading to cardiomyocyte apoptosis may open new routes to prevention and treatment of CHF.
MAPK信号转导通路是一条关键的调节细胞增生和凋亡的通路。
MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.
活性氧通过信号通路介导心肌细胞肥大和凋亡；通过灭活一氧化氮等机制导致内皮功能紊乱。
Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.
线粒体介导了死亡信号通路中自噬与凋亡的相互作用。
There is a mutual regulation between apoptosis and autophagy in death signaling process mediated by mitochondria.
GSK3底物众多，其功能与细胞的存活与凋亡，结构与能动性以及细胞内众多信号传导通路密切相关。
GSK3 regulates many functions including cell survival and apoptosis, structure and motility, intracellular signaling pathways and so on.
AD患者颚叶神经营养因子及其受体表达减少。神经营养因子表达的减少以及存活信号转导通路的损害可能是导致ad脑神经元凋亡的原因之一。
This suggests the diminished expression of NGF and impairment of neuron survival signal transduction pathway may be one of the reason of apoptosis in AD brains.
结论：PM X能诱导NTD的发生，其机制可能是因为PMX阻断了叶酸代谢通路并导致神经上皮细胞的增殖抑制和过度凋亡。
Conclusion: NTD embryos were induced by PMX, the mechanism of which might be PMX inhibited folate metabolism pathway and led to decreased cellular proliferation and excessive cellular apoptosis.
目的探讨泛素-蛋白酶体通路(UPP)在实验性视网膜脱离(RD)中对视网膜细胞凋亡的调控作用。
Objective to investigate the role of ubiquitin-proteasome pathway (UPP) in the regulation of retinal cell apoptosis after experimental retinal detachment (RD).
药物的作用机制尚不清楚，可能的作用包括血管收缩、调节信号传导通路和促进内皮细胞凋亡。
The drugs' mechanism of action remains uncertain, but plausible theories include vasoconstriction, modulation of pro-survival signal transduction pathways, and endothelial cell apoptosis.
介绍褪黑素的合成、代谢通路及其抗氧化、抗细胞凋亡等神经保护作用。
The pathway of synthesis and metabolism, and neuron-protective effect of melatonin were introduced.
近年来在凋亡机制的研究中发现内质网应激反应介导的细胞凋亡是一条新的细胞凋亡信号传导通路。
In recent years, the study found that the apoptosis mechanism of endoplasmic reticulum stress-mediated apoptosis is a new signaling pathway of apoptosis.
结论大花紫玉盘素可能通过线粒体通路诱导细胞凋亡。
Conclusion Uvarigrin induced apoptosis in KBv200 cells and KB cells probably through a mitochondria-dependent pathway.
目的：探讨e2 F1蛋白信号的转导通路对胆管癌细胞凋亡的影响中的作用。
Objective: to study the action of E2F1 protein signal transmission pathway to influence the apoptosis of cholangiocarcinoma QBC939 cells.
目的：探讨e2 F1蛋白信号的转导通路对胆管癌细胞凋亡的影响中的作用。
Objective: to study the action of E2F1 protein signal transmission pathway to influence the apoptosis of cholangiocarcinoma QBC939 cells.
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