细胞内线粒体凋亡途径是凋亡的主要途径之一。
The participation of mitochondria in apoptosis is one of the most important pathways.
结论5f能抑制体外微管蛋白聚合,从而可能是影响细胞的细胞周期及诱导凋亡途径之一。
Conclusion 5f inhibits tubulin polymerization and depolymerization, and leads to cell cycle arrested, and possibly induces apoptosis.
近年来对凋亡发生和调控机制的研究表明,细胞凋亡途径主要有两条:线粒体途径和死亡受体途径。
In recent years, studies of occurrence and regulation mechanism of apoptosis show that the two major apoptotic pathways are the mitochondrial and death receptor pathways.
肿瘤细胞通过多种途径规避凋亡,而机体主要通过这种程序性细胞死亡清除有缺陷的细胞。
Cancer cells have multiple ways to avoid apoptosis, programmed cell death the means by which organisms deal with defective cells.
初始细胞的癌基因的表达往往会通过诱导细胞凋亡、衰老来阻止细胞的增值的,而其实现上述功能的具体途径仍有待澄清。
Expression of an oncogene in a primary cell can, paradoxically, block proliferation by inducing senescence or apoptosis through pathways that remain to be elucidated.
结论EGCG通过活化线粒体信号传导途径诱导BGC823细胞凋亡。
Conclusion EGCG induces apoptosis of BGC823 cells via activating mitochondrial signal transduction pathway.
目的探讨SLE患者免疫功能紊乱与淋巴细胞凋亡信号传导途径异常之间的关系。
Objective To explore the relationship between immune dysfunction and disturbance of lymphocytic apoptosis signal transduction pathway in patients with systemic lupus erythematosus (SLE).
目的:观察薏苡仁提取液对人胰腺癌细胞凋亡和超微结构的影响,以探索胰腺癌治疗的新途径。
Aims: to observe the effects of coix seed extract on apoptosis and ultrastructure of human pancreatic cancer cells, so as to seek a new approach in treating pancreatic cancer.
目的研究曲古菌素A(TSA)诱导髓系白血病细胞株U937细胞凋亡的分子途径。
Objective To investigate the molecular pathway of apoptosis of U937 cells in myelocytic leukemia cell lines induced by trichostatin A(TSA).
然而,所有的这些途径都是通过抑制细胞凋亡的过程和蛋白来维持细胞生存。
All these pathways, however, result in maintenance of cell survival by antagonizing the processes and proteins involved in apoptosis.
目的:探讨全反式维甲酸(ATRA)对人乳腺癌MCF-7细胞凋亡的影响及作用途径。
Objective To investigate the possible pathway of the effect of all-trans retinoic acid(ATRA) on the apoptosis of human breast cancer cell line(MCF-7).
目的评价5脂质加氧酶(5LOX)代谢途径在胃癌中的作用及5 LOX抑制剂对胃癌细胞凋亡的影响。
Aim to evaluate the effect of 5 LOX pathway in gastric cancer and the potential role pharmacological inhibition of 5 LOX on induction of apoptosis in gastric cancer cells.
结论:苦参碱能诱导C6胶质瘤细胞的凋亡,其机制与死亡受体途径和线粒体途径的众多基因有关。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
结论姜黄素可能通过线粒体途径与死亡受体途径诱导鼻咽癌nce细胞凋亡。
Conclusions Curcumin induced apoptosis of NCE cells both through mitochondria-dependent pathway and death receptor pathway.
线粒体与内质网是细胞凋亡信号传导途径中起重要作用的细胞器。
Mitochondria and endoplasmic reticulum are vital cell organs in the process of transmitting apoptosis signs.
进一步阐明心肌细胞凋亡的信号通路,将为CHF的预防和治疗提供新的途径。
Further elucidation of the signal pathway leading to cardiomyocyte apoptosis may open new routes to prevention and treatment of CHF.
而近年来越来越多的研究表明坏死性凋亡是一种不同于凋亡和坏死的新型细胞死亡途径,在多种疾病模型中发挥着重要作用。
However, a growing number of research indicates necroptosis, distinct from apoptosis and necrosis, contributes to a range of human diseases as a new mechanism of cell death.
结论镉诱导HEK293细胞的凋亡可能通过线粒体途径。
CONCLUSION Cd-induced apoptosis involves mitochondrial pathway in HEK293 cells.
热休克蛋白(HSP)对细胞凋亡有双向调控作用,尤其是其抗细胞凋亡的作用为临床多种疾病的治疗开辟了新的途径。
Heat shock protein(HSP) shows both biological effects of up-regulation and down-regulation on apoptosis. Especially the suppressive effects on apoptosis provide a new path to treat various diseases.
目的探讨表没食子儿茶素没食子酸酯(EGCG)通过活化线粒体途径诱导人胃癌BGC823细胞凋亡的作用机制。
Objective to elucidate the mechanism of apoptosis induced by epigallocatechin-3-gallate (EGCG) on human gastric cancer BGC823 cells via mitochondrial pathway.
细胞凋亡的出现较晚,可能使抗凋亡成为治疗脑梗死的一种有效的途径之一。
Anti apoptosis may be one of significant methods for treating cerebral infarction because of delayed apoptosis.
背景与目的:探讨高电压脉冲电场诱导K562细胞凋亡的情况,寻求血液肿瘤治疗的新途径。
BACKGROUND AND AIM: a new approach to kill tumor cells in the blood through investigating apoptosis of K562 cells induced by high intensity pulsed electric fields.
死亡受体通过细胞内信号传导途径可诱导细胞凋亡,与机体的生长、发育、病变和死亡有关。
Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death.
凋亡是个井然有序的过程,大量的分子和途径参与了细胞凋亡发生。
Apoptosis is an ordered process, numerous molecules and approaches are involved in its initiation.
结论PKC在嗜酸细胞凋亡中可以抑制嗜酸细胞凋亡,为治疗因嗜酸性粒细胞增多性疾病的治疗提供新的途径。
Conclusion PKC could inhibit eosinophil apoptosis, and it will provide new methods in treating diseases of eosinophil infiltration and proliferation in fulture.
实验目的:研究内关穴位注射香丹注射液预处理对大鼠心肌缺血-再灌注损伤心肌细胞凋亡线粒体途径的影响。
Objective:To study the effect of pretreatment for mitochondrial pathway of ischemia-reperfusion (I/R) by injecting Xiangdan Zhusheye into PC6.
实验目的:研究内关穴位注射香丹注射液预处理对大鼠心肌缺血-再灌注损伤心肌细胞凋亡线粒体途径的影响。
Objective:To study the effect of pretreatment for mitochondrial pathway of ischemia-reperfusion (I/R) by injecting Xiangdan Zhusheye into PC6.
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