这个令人惊讶的发现促使辉瑞(Pfizer)公司(其收购了里纳特公司)开始研究反其道而行之,将这种药物用来帮助癌症患者或其他受体重减轻困扰的人士增加体重。
The surprising result prompted Pfizer, which acquired Rinat, to explore whether the drug instead could promote weight gain, perhaps for cancer patients or others suffering from wasting.
像许多其他影响神经元放电的物质一样,腺苷必须首先与神经元膜上的特定受体结合。
Like many other agents that affect neuron firing, adenosine must first bind to specific receptors on neuronal membranes.
文章中描述的这种视网膜下植入装置因为比其他类似装置有非常多的光受体,能产生非常高的清晰度。
The subretinal implant described in this paper achieves unprecedented clarity because it has a great deal more light receptors than other similar devices.
这类伽马氨基丁酸受体的抑制药物现正被加州大学的研究小组用于其他方面的临床研究,如失忆,并在一些小的研究上得到了广泛的认同。
The class of drugs used by the UCLA team to block GABA receptors is currently in clinical development for other conditions, such as memory loss, and has been well-tolerated in small studies.
研究发现,孕期中遭到虐待的母亲生下糖皮质激素受体基因被甲基化的幼儿的可能性要比其他母亲高出得多。
They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
同时,其他科学家已经在一组神经元中识别出了一个受体,这个受体能使果蝇闻到二氧化碳,二氧化碳是一顿美味的活酵母呈现的标志。
In the meantime, other scientists had identified a receptor in a group of neurons that enable fruit flies to smell carbon dioxide, which signals the presence of a good meal of tasty yeast.
同时,其他科学家已经在一组神经元中识别出了一个受体,这个受体能使果蝇闻到二氧化碳,二氧化碳是一顿美味的活酵母呈现的标志。
In the meantime, other scientists had identified a receptor in a group of neurons that enablefruit flies to smell carbon dioxide, which signals the presence of a good mealof tasty yeast.
不同的基因产生针对其他癌细胞的受体。
第一步,受体需要这7个关键点的突变使其能够对皮质醇敏感而不再结合其他激素。
In the first, the receptor acquired the seven key mutations that made it sensitive to cortisol and not to other hormones.
后来的4千万年中,这种受体的构想发生改变,变得对皮质醇敏感,而不会结合其他激素。
Over the next 40 million years, the receptor changed shape, so that it became very sensitive to cortisol but could no longer grab other hormones.
“这个受体曾被认为只与细菌有关”Goebeler说,他怀疑其他的过敏原也有同样的行为。
"This receptor was thought to only be relevant for bacteria," says Goebeler, who suspects that other allergens may act in the same way.
除了这些化学受体,这两种田鼠在其他身体构成上几乎完全一致。
Other than those receptors, the two vole species are almost entirely the same in their physical makeup.
这些雄鼠任然保留了肌肉和其他部位的睾丸酮受体,因此他们的身体仍具有阳刚性;研究者通过观察小鼠对迅速增加的和正常循环的激素的反应。
These males still had androgen receptors in their muscles and elsewhere, so they had masculine bodies, and they experienced the testosterone surge and responded to normally circulating testosterone.
首先,他们用基因手段禁止了细胞受体的活动——细胞受体即那些向其他细胞发送和从其他细胞接受信号的分子们——因为雌激素和雄激素存在于正在发育的老鼠胚胎的肢芽中。
First, they used genetic tools to deactivate cell receptors-molecules that send and receive signals to and from other cells-for testosterone and estrogen in the developing limb buds of mouse embryos.
通过对比这种受体和其他相关蛋白,科研人员重建了它的进化历史。
By comparing the receptor to related proteins, the scientists reconstructed its history.
核受体可单独或相互联系而发挥作用,亦可与其他转录因子进行交互通话。
Nuclear receptors can act alone or interact on each other, and they can also crosstalk with other transcriptional factors.
研究大脑其他区域的雌激素受体增加所带来的影响对弄清记忆处理的某些过程有所帮助。
Studying the effects of increasing the estrogen receptor in other brain regions may shed additional light on memory processes.
他们同时还探究了Notch通路怎样影响其他通路,并评估了联合Hedgehog受体抑制剂时的疗效。
They also studied how Notch affects other pathways and evaluated the effects of combined therapy with a Hedgehog inhibitor.
这个发现指明了改善舒缓焦虑的方法,并得以为在不同的神经元回路中,特定之GABA(A)受体子类的其他神经方面失调,开发新药。
This finding suggests ways to improve anxiolytics and to develop drugs for other neurological disorders based on their specificity for GABA(A) receptor subtypes in distinct neuronal circuits.
为了弄清ar -V7的雄激素受体区别与其他,研究者发现实验室生长的前列腺癌细胞只产生AR - V 7序列。
To see how androgen receptors made from AR-V7 differ from others, the researchers forced lab-grown prostate cancer cells to produce only the AR-V7 sequence.
其他一些药物包括H - 2受体阻断剂(雷尼替丁或法莫替丁),可以抑制胃酸的分泌减少胃内容物。
Other pharmacologic agents include the H2-receptor blockers (ranitidine or famotidine), which inhibit gastric acid production and decrease gastric volume.
神经元之间信息传递包括来源于其他神经元释放的化学物质,刺激神经细胞表面受体。
This communication involves the release of chemicals from neurons that stimulate cell surface receptors on other neurons.
还可能与其他药物相互作用,尤其是心血管药物,例如ace抑制剂,受体阻断剂和保钾利尿药。
It can also interact with other medications, especially certain types of cardiovascular medications such as ACE inhibitors, receptor blockers and potassium-sparing diuretics.
其他药物的目的在于通过阻断或激活TRPV 1受体减少疼痛和炎症,这还在研究中。
Other drugs aimed at reducing pain and inflammation by blocking or activating TRPV1 receptors are in the research pipeline.
而细胞内膜受体G蛋白偶联的环磷腺苷浓度促进了细胞的各种功能,也参与调节了其他信号通路。
The concentration of adenosine cyclophosphate of membrane receptor G protein couple stimulates the functions of cells, and participates in regulating various signal transductions.
研究者们发现当用药物将CB 1受体阻断后,小鼠丧失了摄取更多脂肪的兴趣(对其他食物的兴趣依然不减)。
The researchers found that when they blocked CB1 receptors with a drug, rats lost interest in eating additional fat (but not other types of food).
硫酸盐还原菌(SRB)是一类利用硫酸盐或者其他氧化态硫化物作为电子受体来异化有机物质的严格厌氧菌。
Sulfate reducing bacteria(SRB) is one kind of strict anaerobic bacteria that uses sulfate or other oxidative sulfides as electron-acceptors to catabolize organic materials.
当改变DNA链的浓度时,也会有相似的响应,(DNA链)也可以用其他类型的配体-受体对替换,例如抗体。
A similar response is expected by changing the concentration of the DNA tethers, which could also be replaced by other types of ligand-receptor pairs, such as antibodies.
当改变DNA链的浓度时,也会有相似的响应,(DNA链)也可以用其他类型的配体-受体对替换,例如抗体。
A similar response is expected by changing the concentration of the DNA tethers, which could also be replaced by other types of ligand-receptor pairs, such as antibodies.
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