融合素的候选先导药物是西夫韦肽，一种HIV融合抑制剂。
The lead drug candidate in FusoGen's pipeline is Sifuvirtide, an HIV fusion inhibitor.
海洋天然产物已成为发现重要先导药物的主要源泉。
Marine natural products have become one of the most important resources of novel leading compounds especially for the critical diseases.
被美国37个州所采用的三种药物组成的“鸡尾酒”(three - drug cocktail)[3]理应首先导致意识不清，继而肌肉麻痹、呼吸受阻，最后心跳停止。
The three-drug cocktail that is used by 37 American states is supposed first to induce unconsciousness, then to paralyse muscles and block breathing, and finally to stop the heart.
美国制药公司是药物发明的先导，但对消费者来说药价很高，而消费者也越来越知道边界那边的加拿大的药费就低得多。
Us pharmaceutical firms are leaders in innovation, but at a high price to consumers, who are increasingly aware that drug costs just over the border in Canada are considerably lower.
意义该项目将发现有前途的药物先导化合物，阻断黄病毒家族的病毒复制。
This project will discover promising drug leads that stop the replication of viruses within the Flaviviridae family.
天然产物是药物先导化合物的重要来源。
Natural products are one of the most important sources of the lead compounds in drug discovery.
在1981～2002年间批准上市的1 031种药物中，有48％的药物来源于天然产物或与天然的先导结构有关，其中5％的药物为天然化合物的直接应用。
Of the 1 031 new chemical entities covering all diseases in the years 1981-2002, 48% were natural product mimics, 5% were the direct ultility of natural products as sources of novel structures.
可作为抗肿瘤药物或其他生物活性的先导物。
It can be used as anti - tumor medicine and lead matter of other bioactivity.
当代药物设计是通过阐明药物与靶标相互作用的机理，对药物先导化合物进行改造和优化。
Drug design is based on the mechanisms of the drug and target interaction to achieve optimization of the leads.
本发明可为研制新的抗肿瘤药物提供先导化合物，可望成为治疗癌症的药物。
The invention can provide lead compounds for the development of new anti-cancer drugs and is expected to become the drugs for cancer treatment.
本文用支持矢量学习机和神经网络两种机器学习方法建立选择性环氧化酶-2抑制剂的活性预测模型，以期为选择性环氧化酶-2抑制剂药物的合成提供先导化合物。
Machine learning methods, including Support Vector Machines and Artificial Neural Network, are applied to the development of the classification models for the selective COX-2 inhibitors in this paper.
这些工作为利用果蝇模型快速筛选治疗结核病的新药物靶标和药物先导物提供了思路。
These might be helpful to the identification of novel anti-tuberculosis drug targets and lead discovery via the facile Drosophila model.
该文综述了这一领域的主要进展及其在药物研究与开发（如先导化合物的发现和新型诊断与治疗方法的设计）中的应用。
Progress in the field is briefly reviewed and possible application of evolutionary chemistry in drug research and development such as discovery of lead compounds and des…
开发出一批具有新颖结构的黄酮类药物的先导化合物。
This paper systematically summarize current researches in the SAR studies of flavonoids and their derivatives, which can serve as a reference for synthesizing new flavonoid derivatives.
开发出一批具有新颖结构的黄酮类药物的先导化合物。
This paper systematically summarize current researches in the SAR studies of flavonoids and their derivatives, which can serve as a reference for synthesizing new flavonoid derivatives.
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