受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶,在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
在神经发生和早期大脑发育过程中,外切核苷酸酶通常下调嘌呤能信号传导。
During neurogenesis and in early brain development, ectonucleotidases often downregulate purinergic signalling.
在某些情况下特别的变化能触发一个信号——折叠的或方形的状态将激活一些其他的酶,或在细胞中打开一个通道。
In some cases the specific change triggers a signal - the folded or square position may activate some other enzyme, or open a channel in a cell.
治疗过程中的一个步骤需要一种酶,这种酶能促发新陈代谢以及信号转换,从而引发皮肤修复及重塑的进程。
One step in the healing process involves an enzyme that starts a metabolic effect and a signal transduction that triggers the process of skin repair and skin remodeling.
JDRF资助的研究显示,葡萄糖传感信号的酶生产新产生胰岛素的细胞,提示了一条新路的治疗1型糖尿病的可能性。
JDRF-funded study reveals that a glucose-sensing enzyme signals the production of new insulin-producing cells, suggesting a new path of treatment possibilities for type 1 diabetes.
总之,这些结果显示癌细胞如何能通过脂肪分解酶转化脂肪形成一系列具有促癌信号的状态。
Together, these findings reveal how cancer cells can co-opt a lipolytic enzyme to translate their lipogenic state into an array of protumorigenic signals.
体外实验中对相应受体进行刺激后导致对细胞外信号调节酶(ERK)的激活有促进作用。
Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase (ERK).
增加EGR1表达可以激活其他信号分子的转录,包括CDK5和酪氨酸羟化酶,对神经细胞生长和分化有长期影响(2,3)。
Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).
本文综述蛋白酶体在细胞信号转导中的生物学功能和在神经退行性疾病中的可能作用。
This paper reviews the biological functions of proteasome in signal transduction and its potential roles in neurodegenerative diseases.
新的研究发现了一种通过操纵宿主细胞内的一种常见信号通路来破坏早期宿主免疫反应并提高致病性的以前未知的酶反应机制。
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells.
该文从生理、生化、形态定位以及信号转导几方面综述了有关昆虫一氧化氮及其合酶的最新研究进展。
In this paper, advances in research on nitric oxide and its synthase in insects from the perspectives of physiology, biochemistry, morphological localization and signal transduction are summarized.
目的探讨选择性及非选择性环氧合酶-2抑制剂(COX-2)对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
新霉素是一种氨基甙类抗生素,在细胞水平可以抑制磷脂酶c介导的信号转导系统。
Neomycin is one of the aminoglycoside antibiotics, and on the cellular level it inhibits phospholipase c.
目的:研究不同分泌信号对豹蛙酶(ONC)在巴斯德毕赤酵母中分泌效率的影响。
Objective:To investigate the effects of different secretion signals on efficiency of onconase(ONC) secretion in Pichia pastoris expression system.
在一步层析检测中,不需要额外程序(如酶反应)来产生信号的标记是首选的。
Labels that do not require additional procedures (e. g., enzyme reactions) for signal generation are preferred in one-step chromatographic assay.
另外,表面半乳糖基转移酶通过调节表皮生长因子受体信号传导能力向胞内传递生长抑制信号,在细胞增殖控制中起重要作用。
Surface GalTase also delivers a growth inhibitory signal by modulating the ability of the EGF receptor to transduce EGF dependent signals, and plays an important role during cell growth.
单胺氧化酶是一种能分解脑部神经传导物质(信号化学物质)的酶。
Monoamine oxidase a (MAOA) is an enzyme that breaks down neurotransmitters (signaling chemicals) in the brain.
脂氧合酶催化反应生成的氢过氧化物促使信号分子形成的能力与该氢过氧化物的位置特异性及立体旋光性有关。
The ability of LOX products to initiate the synthesis of different signaling molecules is determined by the positional and stereospecific nature of the hydroperoxides produced.
居于此,文中综合评述在突变株分离、酶检测和信号探测等方面,目前的一些常用技术及其最新进展。
In view of these, the authors give here a comprehensive commentary on some common techniques in mutant isolation, enzyme assay and signal detection and their progress recently.
蛋白是一个调节gtp水解酶的超家族,在细胞增殖和分化信号转导过程中发挥关键性作用。
G protein is a superfamily of regulatory GTP hydrolases. They play pivotal roles in the signal transduction of cell growth and differentiation.
在此期间,胃介绍了酸和酶是受许多酶和激素的信号在消化。
During this period, the stomach introduces acid and enzymes which are regulated by many enzymatic and hormonal signals during digestion.
目的研究“酶生物信号放大系统”用于放大dna压电传感器检测信号的可行性和有效性。
Objective to research on the possibility and the efficiency of the enzyme biological signal amplification system applied to DNA piezoelectric biosensor.
除了促进胆囊收缩以外,还可以调节胰酶的分泌和胰腺的生长、胃肠蠕动,抑制胃酸分泌,并参与饱腹信号的传导。
In addition to gallbladder contraction, cholecystokinin also regulates enzyme secretion and growth of pancreas, intestinal motility, satiety signalling and the inhibition of gastric acid secretion.
酪氨酸蛋白磷酸酯酶1 B在胰岛素依赖的信号传导途径中发挥着非常重要的作用,并作为一个潜在的治疗2型糖尿病和肥胖的作用靶点日益受到广泛的关注。
PTP1B plays a very important role in the insulin-dependent signaling cascade and has attracted considerable attention as a possible target for the treatment of type 2 diabetes and obesity.
通过观察碱性磷酸酶对NBT和BCIP的催化反应产生蓝紫色斑点来判定阳性信号。
Positive signals were identified by observing the blue and purple spots produced by the catalytic reaction of Alkaline phosphatase to NBT and BCIP.
蛋白激酶与蛋白磷酸酶在细胞信号传递中起着重要作用。
Protein kinases and phosphatases play a central role in cellular signaling.
注意相对lambda磷酸酶处理(右)细胞未处理细胞(左)中强烈的信号。
Note the robust signal in the untreated cells (left) versus the lambda phosphatse treated cells (right).
注意相对lambda磷酸酶处理(右)细胞未处理细胞(左)中强烈的信号。
Note the robust signal in the untreated cells (left) versus the lambda phosphatse treated cells (right).
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