肥胖症与肝癌:是白细胞介素- 6,信号转导蛋白和转录激活子3的关键作用吗?
Obesity and liver cancer: a key role for interleukin-6 and signal transducer and activator of transcription 3?
如同其它癌症,卵巢癌细胞中的基因发生突变,结果产生了能够改变正常信号转导功能的蛋白。
Genes that are mutated in ovarian cancer, as in other cancers, result in the production of proteins that alter the normal function of signaling pathways in cells.
生物学中的许多现象如细胞凋亡、细胞周期调控、信号转导和癌变等均受蛋白质间相互作用的调控。
Many phenomena in biology, such as apoptosis, cell cycle control, signal transduction and canceration and etc, are all regulated by the interaction of proteins.
结论STAT 3蛋白表达增强可能介导缺血性脑损伤的信号转导过程,其在脑缺血损伤神经元凋亡过程中起关键作用。
Conclusion the expressions of STAT3 increased might indicate the transmission course in ischemic nerve cell signal, and play a key role in neuron apoptosis of ischemic brain injury.
本文综述蛋白酶体在细胞信号转导中的生物学功能和在神经退行性疾病中的可能作用。
This paper reviews the biological functions of proteasome in signal transduction and its potential roles in neurodegenerative diseases.
目标蛋白特定序列和基序的可逆丝氨酸和苏氨酸残基磷酸化是信号转导通路的标志。
A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins.
作为对内质网应激的响应,细胞形成了一条称为未折叠蛋白反应(upr)的自我保护信号转导通路。
In response to er stress, cells have developed a self-protective signal transduction pathway termed the unfolded protein response (UPR).
GA信号转导途径是通过DELLA蛋白来抑止的。
The GA signaling pathway is repressed by the DELLA proteins.
然后进行免疫组织化学染色,观察各组小鼠海马神经细胞存活信号转导通路相关蛋白的表达。
Then immunohistochemistry was used to examine the proteins related to the signal transduction pathways for neuron survival.
受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶,在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
目的:探寻与G_CSF受体胞内区相互作用的下游蛋白因子,揭示G_CSF受体信号转导通路的可能机制。
Objective: to explore the protein factors that may interact with G_CSF receptor in the signal transduction pathways.
信号转导通路是非线性排列的,许多信号转导通路可以通过一系列的蛋白质与蛋白质相互作用形成一个网络。
Among them, the most complex one is the signal transduction. These paths are organized non-linearly, and they can form a network through a series of protein interactions.
颗粒细胞凋亡相关蛋白通过参与凋亡通路及凋亡信号转导调节凋亡。
Apoptosis-associated proteins regulate apoptosis through taking part in the apoptosis pathway and the signal transduction in apoptosis.
蛋白质酪氨酸在一系列细胞活动的信号转导途径中起着重要的作用。
Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions.
目的研究布地奈德(BUD)对支气管哮喘大鼠支气管信号转导子和转录激活子6 (STAT6)基因和蛋白表达的调控作用。
Objective to study the modulation of budesonide (bud) on signal transducer and activator of transcription 6 (STAT6) and its gene expression in the rat model of asthma.
蛋白质激酶的磷酸化级联放大系统在激素的信号转导中起重要作用。
Signalling cascades consisting of protein kinases play important roles in hormone signal transduction pathways of plants.
本文对骨桥蛋白在肿瘤中的信号转导、基因表达与调控以及肿瘤转移过程中的作用予以综述。
This article reviews its role in the signal transduction, expression and regulation in tumors and the roles in tumor metastasis.
人们推测abl蛋白和其他许多看家基因的产物一样,对于正常的信号转导途径并不是必须的。
Presumably, the abl protein, like the product of many other so-called housekeeping genes, is not essential in normal signaling pathways.
信号转导和转录激活蛋白Stat3在细胞的生长、分化、存活和运动过程中扮演重要角色。
Signal transducer and activator of transcription 3 (STAT3) plays a central role in mediating signals related to cell growth, differentiation, survival and movement.
在哺乳动物细胞中,蛋白质的生物合成途径与细胞信号转导途径紧密相连。
These two tRNA synthetases link protein synthesis to a major cell signaling pathway in the given mammalian cells.
结论:针刺能刺激大鼠胃黏膜细胞信号转导通路中蛋白激酶c的活化,并且存在经脉-脏腑的特异性联系。
CONCLUSION: the acupuncture can stimulate the activation of PKC in gastric mucous cell signal conductive pathway of rats, and there is a special correlation between meridian and internal organs.
目的研究罗格列酮联合还原型谷胱甘肽对非酒精性脂肪性肝病(NAFLD)大鼠胰岛素以及胰岛素信号转导相关蛋白表达的影响。
Objective To investigate the effect of rosiglitazone and reduced glutathione on insulin signaling proteins in rats with nonalcoholic fatty liver disease(NAFLD). Methods NAFLD rats were produced.
这种用来选择性地阻断信号转导途径的蛋白激酶抑制剂可能是一种潜在的有利的受体阻断剂。
Electively targeting of signaling pathways using protein kinase inhibitors would have a potential advantage over receptor blockers.
这些蛋白与光合作用、代谢作用、翻译过程及信号转导等关系密切,可能在黄瓜成花中起着不同的作用。
All of these proteins had a close relation to photosynthesis, metabolism, protein translation process and signal transduction. They were playing different parts in cucumber flowering.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导,调节细胞增殖、生长、分化及炎症发生等。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
许多转录因子、细胞内信号转导调节蛋白、炎症细胞因子和细胞凋亡相关基因的表达均发生了明显的调节变化。
The expressions of many genes encoding transcription factor, cytokines, cell signaling modulators and apoptosis associated proteins were found to have changed.
探讨中药固真方对细胞信号转导体系中蛋白激酶活性的影响。
Objective:To study the effect of Chinese herb Vitality Reinforcing Formula on protein kinase activity of cellular signaling transduction system.
研究信号转导途径中蛋白与蛋白之间或者转录因子之间相互作用对于掌握调控机制和分子组成以及揭示生命活动现象的本质有重要意义。
Studies on interactions of protein-protein or transcription will be important to understand the function and constitute of signaling pathway, and the native characteristics of life.
蓝光信号转导涉及隐花色素与其他蛋白质间直接或间接的相互作用。
The signal transformation of blue light involves the direct or indirect interactions between cryptochromes and other proteins.
蓝光信号转导涉及隐花色素与其他蛋白质间直接或间接的相互作用。
The signal transformation of blue light involves the direct or indirect interactions between cryptochromes and other proteins.
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