笔者讨论了一些五环三萜类化合物的药理活性与结构的关系。
This article is reviewing the structure-activity relationship of pentacyclic triterpenes.
目的:对天然五环三萜进行结构修饰,寻找新型糖原代谢调控药物。
Aim: to search for novel modulators of glycogen metabolism through structural modifications of natural pentacyclic triterpenes.
典型的标志如卟啉、姥鲛烷、植烷、留烷、胡萝卜烷、以及五环三萜烷。
Typical markers are the porphyrins, pristine, phytane, steranes, carotenes and pentacyclic triterpanes.
熊果酸属于五环三萜类化合物,广泛存在于天然植物中,具有多种显著的药理活性。
Ursolic acid, a pentacyclic triterpene compound, naturally occurs in a large variety of plants, has attracted considerable interest owing to its significant biological activities.
五环三萜是一类重要的天然产物,研究发现生物转化能够对该类化合物进行多种类型的结构修饰。
Pentacyclic triterpenes are among the most important bioactive compounds and biotransformation is a very useful tool to carry out the structural modification on these compounds.
其主要功能成分是人参皂苷,即达玛烷型四环三萜类或香树脂烷型五环三萜类化合物,至今人参皂苷尚未能人工合成。
Ginsenoside, the main components of ginseng, is dammarane tetracyclic triterpenoids or hong resin alkyl type pentacyclic triterpene, which has not yet been synthesized artificially.
五环分别为蓝、黑、红、黄、绿色,三环在上,两环在下,环环相扣,紧紧联在一起。
Five links be blue, black, are respectively red, yellow, the green, three links in on, two links in under, are linked together, tight association in same place.
五环分别为蓝、黑、红、黄、绿色,三环在上,两环在下,环环相扣,紧紧联在一起。
Five links be blue, black, are respectively red, yellow, the green, three links in on, two links in under, are linked together, tight association in same place.
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