• 笔者讨论一些五环萜类化合物药理活性与结构的关系

    This article is reviewing the structure-activity relationship of pentacyclic triterpenes.

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  • 目的:对天然五环进行结构修饰寻找新型糖原代谢调控药物。

    Aim: to search for novel modulators of glycogen metabolism through structural modifications of natural pentacyclic triterpenes.

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  • 典型标志如卟啉、姥烷、植烷、留烷、胡萝卜烷、以及五环三烷。

    Typical markers are the porphyrins, pristine, phytane, steranes, carotenes and pentacyclic triterpanes.

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  • 熊果酸属于五环萜类化合物,广泛存在于天然植物中,具有多种显著药理活性

    Ursolic acid, a pentacyclic triterpene compound, naturally occurs in a large variety of plants, has attracted considerable interest owing to its significant biological activities.

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  • 五环是一类重要天然产物,研究发现生物转化能够该类化合物进行多种类型的结构修饰

    Pentacyclic triterpenes are among the most important bioactive compounds and biotransformation is a very useful tool to carry out the structural modification on these compounds.

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  • 主要功能成分人参苷,即达玛四环萜类树脂烷型五环萜类化合物,至今人参皂苷尚未能人工合成

    Ginsenoside, the main components of ginseng, is dammarane tetracyclic triterpenoids or hong resin alkyl type pentacyclic triterpene, which has not yet been synthesized artificially.

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  • 五环分别绿色上,在下环环相扣紧紧联在一起。

    Five links be blue, black, are respectively red, yellow, the green, three links in on, two links in under, are linked together, tight association in same place.

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  • 五环分别绿色上,在下环环相扣紧紧联在一起。

    Five links be blue, black, are respectively red, yellow, the green, three links in on, two links in under, are linked together, tight association in same place.

    youdao

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