不过，确实出现了一个重大问题。
根据一项调查，学生的安全已经成为一个重大问题。
According to a survey, students' safety has become a big problem.
如何保持可持续发展是所有国家面临的一个重大问题。
How to maintain sustainable development is a matter of significant importance facing all countries.
问:中毒也是一个重大问题吗？
但是还有一个重大问题没有回答。
容纳不同的数据库是一个重大问题。
不过，确实出现了一个重大问题。
这是许多人关心的一个重大问题。
这是许多人关心的又一个重大问题。
报纸能否办下去是一个重大问题。
There's a very large question about the viability of the newspaper.
那是我发现的一个重大问题。
荒漠化是关系到我国民生的一个重大问题。
In our country, desertification becomes an urgent problem influencing people 'life.
然而，土地问题是影响许多社区的一个重大问题。
Land issues, however, are a significant problem affecting many communities.
而我们今天正在钻研的一个重大问题就是汽车的安全性和效率。
And one of the big problems we're working on today is car safety and efficiency.
贫困问题始终是困扰人类社会进步的一个重大问题。
Poverty is always a big problem which perplex the development of society.
我们认为，这是我们下一步的工作是解决一个重大问题。
We feel, and this is our next step is to solve a major problem.
如何治理和整顿虚假广告是当前亟待解决的一个重大问题。
新生儿死亡率即是如此，这是我们需要处理的又一个重大问题。
This is the case with newborn mortality, another big problem we need to address.
有效桩长是柔性桩复合地基设计时需要考虑的一个重大问题。
Effective pile length is an important problem that should be thought about when making a design of flexible piles composite foundation.
山姆，我很抱歉给你打电话，但是生产线上出现了一个重大问题。
Sam, I am sorry to call you, but a major problem with the production line has come to light.
因此，跨文化人力资源管理已经成为大陆台资企业的一个重大问题。
Therefore, the across-cultural human resource management turns into a very important issue of them.
如何对员工的绩效进行考核，是企业治理者所面临的一个重大问题。
How to undertake assessing to the performance of employee, it is business management person a when be faced with major problem.
在这种状况下，如何合理利用土地已成为摆在人们面前的一个重大问题。
In this condition, how to use land reasonably is a very important problems faced by people.
国企青年员工流失率上升已成为企业人力资源管理面临的一个重大问题。
The increasing loss rate of young working staff among state - owned enterprises has become an important problem that human resource management is faced with.
增加铁和铜的氧化应激(自由基损伤)，这是一个重大问题在CFIDS。
Iron and copper increase oxidative stress (free radical damage), which is a major problem in CFIDS.
寻找和培育新的经济增长点已成为我国近期宏观经济管理的一个重大问题。
To find and cultivate new points of economic growth has become a critical issue in our country's macroeconomic management.
测试用设备不合适也可能是一个重大问题，因此，需从值得信赖的供应商处购买。
Testing with equipment that is not appropriate can be a major problem so also buy from a trusted vendor.
测试用设备不合适也可能是一个重大问题，因此，需从值得信赖的供应商处购买。
Testing with equipment that is not appropriate can be a major problem so also buy from a trusted vendor.
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