麦普替林,别名:路滴美 也译作 马菩提林;本品为广谱抗抑郁药,抗抑郁效果与丙米嗪,阿米替林相似,但奏效快、副作用少服药后精神症、对环境的适应能力、及自制力均有改善,安定作用睡眠改善,用于迟钝型抑郁症,也适用于激越型抑郁症,有抗组胺及抗胆碱作用亦用于疾病或精神因素引起的焦虑、抑郁症。
两组有明显差异,提示麦普替林对癌症患者的抑郁情绪有明显疗效。
There was significant difference between the 2 groups, it suggested that maprotiline had evident effect on the depressive emotion of the patient with cancer.
去甲麦普替林、活性部分的浓度高于阈浓度时,会增加出现不良反应的可能。
When the concentrations of N-demethylmaprotiline and active moiety are higher than threshold concentration, the possibility of side effects may be increased.
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