病灶部位的巨噬细胞细胞聚集、增生。当他们吞噬纤维素坏死物后，转变成风湿细胞或阿少夫细胞（Aschoff cell）。风湿细胞体积大，圆形、多边形，边界清楚而不整。胞浆丰富均质而微嗜双色。核大，圆形或卵圆形，核膜清晰，染色质集中于中央，横切面呈枭眼状，纵切面呈毛虫状，稍后则核变得浓染结构不清。
它组成成份是风湿细胞，体积大，可有双核或多核（核仁很明显）。
The most characteristic component is the Aschoff giant cell. Several appear here as large cells with two or more nuclei that have prominent nucleoli.
Rituxan现在已经被批准用于非霍奇金淋巴瘤、慢性淋巴细胞白血病和风湿性关节炎的治疗。
Rituxan is currently approved as a treatment for non-Hodgkin's lymphoma, chronic lymphocytic leukemia and rheumatoid arthritis.
青藤碱的抗类风湿作用可能与其抑制树突状细胞分泌白细胞介素12有关。
The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs.
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