颗粒性抗原如各种细胞、细菌、寄生虫等皆为颗粒性抗原。 细胞抗原(如绵羊红细胞)一般情况下经过生理盐水或其他溶液洗净,配置一定浓度即可。细菌抗原多用液体或固体培养物,经集菌后处理。 颗粒性抗原大多用静脉内注射免疫法,较少加佐剂作皮内注射。
标记抗体与包涵体相结合,包涵体为颗粒性抗原所在之处。
Injected labeled antibody combined with antigen in the inclusion body. Inclusion body is the site of granular antigen.
这样他制造了一个抗原呈递细胞的副本,这个颗粒可以反复的激活抑制性T细胞,使他们增殖并杀死真正的抗原呈递细胞。
In doing so, he created an APC doppelganger that could repeatedly activate the weak t cells, causing them to proliferate and kill the real APCs.
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