本发明还涉及可用于该方法的非磷酸化的IGFBP。
The invention also relates to non-phosphorylated IGFBPs useful in the methods.
非磷酸化的MKK3/MKK6细胞提取物： 未经处理的NIH/3T3细胞总提取物，作为阴性对照。
Nonphosphorylated MKK3/MKK6 Control Cell Extracts: Total cell extracts from NIH/3T3 cells, prepared without treatment, serve as a negative control.
接着，我们检测配体依赖的基于受体表达，磷酸化，二聚化的细胞对吉非替尼敏感的机制。
Subsequently, we monitored the ligand-dependent HER profiles based on receptor expression, phosphorylation, and dimerization in conjunction with measurements of cellular susceptibility to gefitinib.
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