目的探讨结直肠癌肿瘤实质及肿瘤间质中基质金属蛋白酶- 2 (MMP - 2)的表达及其病理学意义。
Objective To evaluate the expression of Matrix metalloproteinase 2 (MMP 2) in colorectal tumor epithelial cells and mesenchymal cells.
逆转录多聚酶链反应检测间质胶原酶及金属蛋白酶组织抑制因子- 1基因表达水平。
The gene expression levels for interstitial collagenase and tissue inhibitor of metallo-proteinase-1 (TIMP-1) were measured by reverse transcription polymerase chain reaction.
目前，已经知道破骨细胞是导致关节侵蚀的主要细胞，而基质金属蛋白酶9 (MMP - 9)在破骨细胞中高表达，在细胞外间质的降解中发挥重要作用。
It is known that osteoclast is the main ce ll causing osseous erosion, while matrix metalloproteinase-9 highly expressed in osteoclast, plays an important role in extracellular matrix degradation.
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