选用治疗脑中风等疾病疗效确切的中药活性成分银杏内酯B(Ginkgolides B)作为脑靶向制剂的模型药物。银杏内酯是一类由银杏中分离出的天然产物,包括银杏内酯A、B、C、J、K等。
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摘要: 目的 了解银杏内酯B(GKB)对癫痫大鼠海马中低氧诱导因子-1α(HIF-1α)与磷脂酰肌醇-3激酶/丝氨酸-苏氨酸蛋白激酶(PI3K/Akt)的影响,并探讨在这个过程中两者...
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)2.36%总内酯Total Lactones≥6%6.84%其中白果内酯BB(Bilobalides)2.67%银杏内酯A(Lactones A)1.99%银杏内酯B(Lactones B)1.32%银杏内酯C(Lactones C)0.86%银杏酚酸Ginkgolic Acid<5ppm<3.22ppm铬Chromium<0.1ppm<0.08ppm铅Pb<0.5ppm<0.32pp...
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...银杏内酯B;海马神经元活性;突起生长 [gap=1453]Key words】 Alzheimer′s disease;Cholesterol;Apolipoprotein E4;Ginkgolide B;Activity of hippocampi neurons;Neurite outgrowth ..
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Meanwhile, Ginkgolide B (800μg/ml)inhibited the expression of phosphorylation of NOX4 induced by 0.01% H2O2.
⑤0.01% H2O2刺激血小板细胞使NOX4磷酸化水平增加,银杏内酯B(800μg/ml)有效抑制了H2O2诱导的NOX4磷酸化。
参考来源 - 银杏内酯B抗增龄血小板聚集作用的分子机制研究In this paper, endophytic fungi of Ginkgo biloba L. were studied, from which the ginkgolideB-producing strains were screened orientationally, by means of analyzing their cellular metabolites from trial-strains, and its cultivation conditions were optimized.
本文以银杏内生真菌为研究对象,通过对内生真菌次级代谢产物的研究,定向筛选银杏内酯B产生菌,并对其进行液态培养条件的优化。
参考来源 - 产银杏内酯B内生真菌的筛选及培养条件优化·2,447,543篇论文数据,部分数据来源于NoteExpress
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