目的构建重组人瘦素哺乳细胞表达载体并在COS 7细胞表达重组人瘦素。
Objective to construct recombinant human leptin mammalian cell expression vector, and to express recombinant human leptin in COS-7 cells.
结论构建了人瘦素的哺乳动物细胞表达载体，并成功地在COS 7细胞中获得重组人瘦素的分泌表达。
Conclusion Cloning and expression recombinants of human leptin are obtained and secretive recombinant human leptin is successfully expressed in COS-7 cells.
血液透析病人血瘦素与BMI呈正相关，但重组人促红细胞生成素治疗可使两者相关性消失。
Leptin was positively correlated with BMI in HD patients, and EPO therapy can make the relationship disappear.
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