本课题中我们应用端粒酶逆转录酶启动子(htert promoter)的肿瘤特异性特异性树立一种特异性表达siRNA的体系,将siRNA表达局限在肿瘤细胞中,而在正常细胞中不表达。
基于12个网页-相关网页
端粒酶启动子 hTERTp
酶-启动子二元复合物 closed binary complex
碱性磷酸酶启动子 phoA promoter
醇脱氢酶启动子 alcohol dehydrogenase promoter ; ADHP
乙醇脱氢酶启动子 alcohol dehydrogenase promoter ; ADHP
磷酸甘油激酶启动子 phosphoglycerate kinase promoter
酸甘油激酶强启动子 PGKP ; phosphoglycerate kinase promoter
因此端粒酶的启动子 human telomerase reverse transcriptase promoter
目的研究TRAIL基因结合端粒酶启动子特异性靶向治疗的作用。
To explore the targeted gene therapy of tumors by using the TRAIL gene in combination with the telomerase promoter.
目的：研究TRAIL基因结合端粒酶启动子特异性靶向治疗的作用。
AIM: To explore targeted gene therapy of tumor by using the combination of TRAIL gene with the telomerase promoter.
目的：研究凋亡因子TRAIL结合端粒酶启动子对肿瘤的特异性杀伤作用。
OBJECTIVE: to investigate the specificity role of the apoptosis factor TRAIL gene with telomerase promoter in tumor gene therapy.
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