大量使用者已经患上了PML，这是一种脑部退化疾病，它造成十多人死亡，并使很多人病情恶化且终生残疾。
Scores of users have developed PML, a devastating brain disease that has left a dozen dead and many more badly and permanently disabled.
除上述趋势以外，基础设施的退化，教育相对表现的恶化，以及糟糕的税制都构成挑战。
In addition to the trends identified above, deteriorating infrastructure, worsening relative educational performance and a terrible tax code are challenges.
冲刺（短距离）运动员恢复过程中的一个最重要的部分，是要足够的休息，以使得肌肉得到充分的恢复，但是也不能休息太多，使得情况恶化（肌肉退化）。
One of the most important parts of a sprinter's taper is finding the balance between resting enough for the muscles to adequately recover, but not so much that they begin to deteriorate.
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