采用大鼠脑组织立体定位微量注射技术造模，连续给药三周，然后利用水迷宫和跳台实验观察其学习记忆能力。

After treating for three weeks, channel water maze task and step-through task were used to observe the ability of learning and memory.

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方法用空肠弯曲菌免疫小鼠制备自身免疫病模型，造模第二周起，分别用小、中、大三个不同剂量黄柏的大补阴丸（汤）灌胃，连续用药两周后处死。

Methods Autoimmune mice models induced by CJ were used as experimental objects. From the second week after immunization to the fourth week , the mice were given DBYW with different dosages of CP .

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