这些结果具有重要意义，因为多环芳烃二醇环氧化物极易与DNA反应，进而导致变异，因此被视为香烟烟雾中所含多种多环芳烃中最重要的致癌物质。
These results are significant because PAH diol epoxides react readily with DNA, induce mutations, and are considered to be ultimate carcinogens of multiple PAH in cigarette smoke.
这种病的特点是，一段名为RPE65的基因发生变异，导致缺失，进而引起视网膜退化，大脑视觉处理中断。
It is marked by a mutation in a gene known as RPE65 which results in a missing enzyme that leads to degradation of the retina and the disruption of vision processing in the brain.
现在看来这种家畜用药导致了菌种的变异并已经被进而传递给人类。
It seems highly likely that the medication of farm animals led to the evolution of the strain that has since been passed to people.
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