目的表达白喉毒素无毒变异体CRM197,并考察其载体作用。
Objective To express the nontoxic mutant CRM197 of diphtheria toxin and study its effect as a carrier protein.
理想的纳米粒载体应有特异靶向性、药物释放可控性,无毒性以及可生物降解等。
The perfect nanoparticle vectors should be specific-targeting, controlled release, nontoxicity? biodegradation, and so on.
结论活性炭有较强的趋淋巴性,在淋巴结中驻留时间长,其本身无毒性,可作为淋巴结示踪剂及药物载体。
Conclusions the activated carbon can be used as a useful lymphatic tracer and drug carrier, for it is characterized by avirulence, high lymphatic tropism, long residence time in the lymph nodes.
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