SiHa 细胞; STAT3; RNA干扰; 增殖; 凋亡 信号转导子及转录活化子（signal transducers and activators of transcription, STATs）是细胞因子和生长因子受体信号的下游效应物, 在细胞核内与特异性的...
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结果该质粒有正确的阅读框，其表达蛋白不具有自主转录激活作用，与已知核受体辅活化子PNRC有明显的相互作用。
Results The protein expressed by the plasmid which had a correct reading frame, had no transcriptional activation and could interact with a known coactivator PNRC.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2（TIF-2），ARA24、PIAS、类固醇受体辅活化子-1（SRC-1）等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
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