另人吃惊的是,这个因子证明是具有一般转录抑制因子nc2的明显的特征。
Surprisingly, the factor turns out to have been previously characterized as a general repressor of transcription, NC2, an observation explained by its ability to repress TATA-box-containing promoters.
PML是一个生长和转录抑制因子,研究表明PML表达变化可能和一些实体癌的发生有关。
PML is a growth and transformation suppressor, and it may play a role in the oncogenesis of solid tumors.
一个独特的转录因子网络可能赋予其自我更新,同时抑制分化。
A unique network of transcription factors might characterize self-renewal and simultaneously suppress differentiation.
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