就是在这一步，使一项发现转化为安全有效的可生产的药物成为死亡之谷，尤其是近几年来更为致命。
It is at this step-turning a discovery into something that can be manufactured and that is safe and effective-that the valley of death has gotten dramatically more fatal over the last few years.
我在我们医院中看到越来越多的急性酒精性肝炎（日后大都转化为肝硬化）患者，他们会导致各种疾病的发病率和死亡率的升高，同时也消耗掉了许多宝贵的健康资源。
An increasing number of severely ill acute alcoholic hepatitis patients, often superimposed on cirrhosis, are being seen in our hospitals and cause much morbidity, mortality and health service costs.
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