正常角膜上皮被结膜上皮侵犯和替代为特征,即“角膜缘干细胞缺乏” (limbal stem cells deficiency):损伤造成、基质微环境异常 。 眼表疾病的治疗原则 眼表的正常与稳定是维持角膜透明性的重要保证。
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角膜缘干细胞缺乏将导致各种眼表功能异常。
The lack of limbal stem cells results in many abnormalities of ocular surface function.
角膜上皮的增生与更新依赖于角膜缘干细胞,角膜缘干细胞缺乏可导致视力障碍。
The proliferation and refreshment of corneal epithelium depends on corneal limbal stem cells. Corneal limbal stem cell deficiency can lead to visual disorder.
目的:用体外培养的角膜缘上皮细胞联合人羊膜的方法,行自体移植治疗角膜缘干细胞完全缺乏的兔眼。
Objective: to study in vitro cultivated limbal epithelial cells autograft with amniotic membrane grafts for total limbal stem cell deficiency of rabbit eyes.
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