抑制程度基本取决于他们的浓度，给药频率，患者的体表面积和皮肤的屏障能力。
The extent is generally related to their potency, frequency of application, the patient's body surface area, and the skin's ability to act as a barrier.
经皮给药是将药物贴敷在皮肤外表面，依靠被动扩散或促进扩散使药物通过皮肤进入皮下毛细血管。
TDD is the method that patching the drug on the skin, the drug molecules permeating through the skin into the subcutaneous capillary vessels by passive diffusion and enhanced diffusion.
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