单独使用三种药都要抑制APL和ALL细胞株的生长但不会直接导致细胞死亡,而联合使用可以引起表型分化。
ALL three drugs inhibited the clonogenic growth of the APL and ALL cell lines without inducing immediate apoptosis, but associated with induction of phenotypic differentiation.
结论雌激素可能通过抑制UUO大鼠肾小管上皮细胞表型转化而发挥延缓肾间质纤维化的作用。
Estrogen can prevent the development of interstitial fibrosis, the mechanism may with it restrain the tubular epithelial cell phenotype transdifferentiation in UUO rats.
结论:外源性CAR基因的导入可以增强卵巢癌细胞SKOV3间的粘附性,从而抑制肿瘤细胞的侵袭转移表型。
CONCLUSION: Transfected CAR gene may enhance the adhesion ability of ovarian cancer SKOV3 cells, therefore, inhibit the malignant metastatic phenotype of SKOV3 cells.
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