国产氯吡格雷治疗急性冠脉综合征的有效性和安全性_药学论文 关键词] 血小板抑制剂;氯吡格雷;急性冠脉综合征;血栓 [gap=1102]Key words] Platelet inhibitor; Clopidogrel; Acute coronary syndrome; Thrombosis
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血小板聚集抑制剂 platelet aggregation inhibitors
血小板粘附抑制剂 Platelet adhesion antagonists
抗血栓形成药[血小板聚集抑制剂]的有害效应 Adverse effects in therapeutic use, antithrombotic drugs
背景:血小板对氯吡格雷的反应性存在异质性,而且以氯砒格雷作为次选血小板抑制剂的临床或生物化学预测尚不清楚。
Background: a heterogeneous platelet reactivity response to clopidogrel exists, and the clinical or biochemical predictors of suboptimal PI with clopidogrel remain unclear.
但是近期的报道已经表明两种药物之间有潜在危险的相互作用,由此质子泵抑制剂降低抗血小板药物的实际效果。
But recent reports had suggested that there might be a potentially dangerous interaction between the two drug classes whereby PPIs reduce the actual effectiveness of antiplatelet agents.
结果发现毛果芸香碱也是血小板聚集的抑制剂。
The results showed that pilocarpine was also an inhibitor of platelet aggregation.
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