...一过程称为结合反应,又 称Ⅱ相生物转化反应(PhaseⅡ Biotransformation) 20 一、葡萄糖醛酸结合(Glucuronic Acid Conjugation) 药物或其代谢产物与葡萄糖醛酸结合是药物 代谢中最常见的反应。其结合过程分两步进 行。
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结论不成熟大鼠肝脏葡萄糖醛酸转移酶1 A 1活性很低,导致此期的胆红素葡萄糖醛酸结合反应水平低下。
Conclusions UGT1A1 activity in the liver of premature rat is very low, so the bilirubin glucuronidation level is low in this period.
对尿样中甾体葡萄糖醛酸甙结合物的酶促水解条件也进行了初步探索。
The enzymatic hydrolyzation of conjugated steroids in human urine has also been investigated.
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