蛋白和配体间的作用通常是通过弱非共价键力的相互作用而实现的，如疏水作用、范德华力和氢键。
The binding of ligands to proteins occurs mostly through weak non-covalent interactions, namely hydrophobic interaction, van der Waals forces, and hydrogen bonding.
氢键不属于化学键，也不属于范德华力，是介于化学键和范德华力之间的一种由氢原子参与成键的特殊键型。
The hydrogen bond does not belong to the chemical bond, neither belong to the van der Waals force. It is a special kind of bond situated between the chemical bond and the van der Waals force.
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