人们预期通过其他病毒,例如引起风寒的腺病毒,来制作疫苗。多年的失败后,人们想到了HIV本身。
The idea of turning to the virus itself follows years of frustration with prospective vaccines based on viruses other than HIV, such as adenoviruses that cause colds.
当时,医生们仅仅披露,使用“腺病毒”或者感冒病毒将HIV的基因植入人体的疫苗没有发生作用。
At the time, doctors revealed only that the vaccine-which USES an "adenovirus," or the common cold virus, to deliver HIV genes into the body-had not worked.
目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。
Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.
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