out of one's mind ; brain-damaged
你看起来脑子坏了。
You look so distraught!
youdao
俄国也被从另一扇玻璃窗扔了出去，但受了伤，脑子坏了，醒了之后性格大变。
Russia gets thrown through another one, gets knocked out, suffers brain damage, and wakes up with a complete personality change.
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