通过腺病毒载体介导使多药耐药基因转染入脐血有核细胞,提高其对化疗药物的耐受性。
MDR1 gene was transfered to cord blood nucleate cells (CBNC) mediated by adenovirus vector, for enhancing its resistance to chemotherapeutic drugs.
方法在相同细胞因子组合下,用体外液体培养比较脐血有核细胞程序扩增组与一次扩增组及有无基质层条件下的优劣。
Methods under the same condition with hematopoietic factors in the liquid culture, compared the sequential expansion group and once for all expansion group with or without stroma cell layer.
脐血移植有核细胞重建时间与输入的有核细胞数以及疾病类型相关,同HLA相合程度不相关。
The time of nuclear cell reconstitution after cord blood transplantation was statistically related with nucleated cells and the type of disease, not related with HLA matching.
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