世界华人消化杂志 Key Words: MicroRNAs; Stem cell differentiation; Pancreas development [gap=448]关键词: microRNA; 干细胞分化; 胰腺发育
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胚胎胰腺发育 embryonic pancreatic development
胰腺不发育 pancreatic agenesis
胰腺缺如、不发育和发育不全 Agenesis, aplasia, and hypoplasia of pancreas
Overall, these results indicate that miR-18a, miR-145 and miR-495 can repress Ptfla expression and participate in a Ptfla related regulatory pathway during pancreatic development in mouse.
综上所述,本研究证明miR-18a,miR-145和miR-495可抑制Ptfla的表达,并参与到小鼠胰腺发育中Ptfla相关的调控网络中。
参考来源 - MiRPancreatic duodenal homeobox-1,PDX-1,as a important transcription factor in pancreas development, directs the normal development of pancreas and can regulate a number of genes involved in maintaining beta-cell identity and function.
胰腺-十二指肠同源框1（pancreatic duodenal homeobox-1，PDX-1）作为胰腺发育过程中重要的转录因子指导胰腺的正常发育。
参考来源 - 胰腺发育相关基因PDX·2,447,543篇论文数据，部分数据来源于NoteExpress
他们发现了四个新的与胰岛素分泌和胰腺发育有关的新的基因区域。
They found four new areas that appear involved in insulin secretion and pancreatic development.
目的：探讨与胰岛形成和功能完善相关的基因在大鼠胰腺发育不同阶段的表达趋势。
AIM: to investigate the expression profile of genes related to islet formation and maturation during pancreas development.
认为胰腺因坏死而发育迟缓甚至停滞，致其体积变小。
The pancreas stunt and even stagnating were due to its acini necrosis, which made its size smaller.
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