目的探讨胎粪性肠梗阻的诊断和治疗方法。
Objective To discuss methods of diagnosis and treatment in meconium ileus.
新生的缺乏CFTR基因的猪表现出氯化物转移缺陷,胎粪性肠梗阻,胰腺外分泌缺陷和局限性胆道硬化,而这些症状正是人类CF疾病的主要症状。
Newborn pigs lacking CFTR showed defective chloride transport and developed meconium ileus, exocrine pancreatic destruction, and focal biliary cirrhosis, which are all hallmark of CF disease.
临床表现为患儿胎粪排出延迟,顽固性便秘和腹胀,常并发小肠结肠炎、低位性肠梗阻,严重者危及患儿生命。
Delay to excrete meconium, refractory constipation and abdominal distension are commonly seen, also commonly accompanying with enterocolitis in small intestine and colon, lower intestine obstruction.
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