LKB1,也称STK11,是一种丝氨酸/苏氨酸蛋白激酶,也被认为是一种肿瘤抑制因子(tumor suppressor),可以通过调控多种下游的激酶,来调节细胞结构、细胞凋亡和能量代谢平衡。
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... super-suppressor 释义:超抑制因子,超抑制基因 tumor-inhibiting factor 释义:肿瘤抑制因子 autoinhibiting factor 释义:自身抑制因子 ...
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一种肿瘤抑制因子抗体 Anti-VHL
肿瘤抑制因子的振动性 oscillations of the tumor suppressor
一种肿瘤抑制因子 Anti-VHL
称为多种肿瘤抑制因子 MTS ; multiple tumor suppressor
肿瘤血管生成抑制因子 angiogenesis inhibitor
肿瘤坏死因子抑制剂 TNF inhibitors ; Tumor Necrosis Factor Blockers
肿瘤细胞抑制因子 cartilage antitumor component ; CATC
肿瘤转移抑制因子 NM ; non- metastasis
肿瘤坏死因子抑制蛋白 tumor necrosis factor inhibitor protein
这一新的解释把以往关于BCA1作用机制各不相干的理论整合到一起,对其他肿瘤抑制因子作用机制的了解可能带来帮助。
This explanation brings together many disparate theories about how the gene functions and could also shed light on how other tumour suppressors work.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达,但并不是通过基因突变或促进子甲基化而实现的,因此其失表达的机制还不清楚。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
类似的相反作用在其他肿瘤抑制因子中也有发现,但H - REV107 - 1的表达与非小细胞肺癌病人存活期的关联还是相当令人震惊。
Similar reverse functions have been identified for other tumor suppressors, but the correlation between H-REV107-1 expression and NSCLC patient survival is quite striking.
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