（四）肾小管-间质损伤 (Renal tubule-interstitium injury) 残存肾单位的肾小管，尤其是近端肾小管，在慢性 肾衰竭时发生代谢亢进，细胞内钙含量增多，自由基产 生增多，导致肾小管和间质细...
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肾小管间质损伤 tubulointerstitial lesion ; TIL
患者肾小管间质损伤 tubulointerstitial lesion ; TIL
和肾小管间质损伤指数 tubulointerstitial index ; TII
与肾小管间质损伤指数 tubule interstitial score ; TIS
及肾小管间质损伤指数 tubulointerstitial injure index
引起肾小管间质病变的原因比较复杂，其中蛋白尿的肾损伤作用已为大量临床和实验研究所证实。
The causes for tubulointerstitial changes remain rather complex and the role of proteinuria in damaging nephridial tissue has been demonstrated by large number of clinical and experimental studies.
结果：肾小球系膜区FN与系膜细胞增生、肾小球损伤程度及肾小管间质损伤程度均呈正相关。
Results Positive correlations were found between the degree of FN in glomerular mesangium or basement membranes and glomerular lesion grading or tubulointerstitial lesion grading.
肾间质纤维化；肾小管上皮细胞；线粒体氧化损伤；肾小管功能。
Renal interstitial fibrosis; Renal tubular epithelial cell; Mitochondria oxidative damage; Renal tubular function.
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