目的探讨GAD抗原肽抗体诱导特异性免疫耐受对IDDM糖尿病的基因治疗。
Objective Gene therapy with GAD-IgG tolerogens that induces specific tolerance to IDDM.
抗体由蛋白A和肽段亲和层析纯化得到。
Antibodies are purified by protein A and peptide affinity chramotography.
单克隆抗体通过用对应于人源PDHK1蛋白序列的合成肽免疫动物制备而得。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human PDHK1 protein.
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