伍特谈到，肥胖是另一个主要危险因子。

Voute says obesity is another major risk factor.

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以前找到的很多都是能够导致人肥胖的基因，而“瘦身”基因是首例发现的可以让人变得异常苗条的遗传因子。

While many genes have been identified as leading to obesity, this is the first time a genetic explanation for 'extreme thinness' has been unveiled.

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该团队分析重点在于热量摄入和一种叫做胰岛素样生长因子（IGF -1）的蛋白质之间的联系，随着肥胖增加，限制热量摄入水平将降低IGF - 1 。

The group's analysis points to a connection between calorie intake and a protein called Insulin-like Growth Factor (IGF) -1, with obesity increasing and calorie restriction decreasing levels of IGF-1.

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