首要终点指标是生存期,次要指标包括肿瘤缓解、症状改善、体重变化、肝功能改善等。
Primary destination indicator is survival, secondary indicators include tumor response rate, symptoms improvement, weight change and liver function improvement.
结果:对照组大鼠肝功能改善缓慢,ALT,AST明显高于移植组(P<0.05),移植组大鼠损伤的肝组织逐渐修复,肝功能恢复正常。
Results: The liver function of control group was slow recovery, as evidenced by significantly increased ALT and AST in serum(P<0.05).
结论拉米呋丁治疗活动性肝硬化效果良好,可使肝功能明显改善。
Conclusion Adding lamivudine has better curative effect on treating active hepatocirrhosis and improving the function of liver.
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