或许这些患者存在完全不同的问题，不是耐药毒株，而是活性很高的能阻止干扰素应答的毒株。
Maybe these patients have a totally different problem-not a resistant strain, but a strain that is actively blocking interferon response.
目前流行的一些H5N 1毒株对这些M2抑制剂有完全的耐药性，然而，如果新的病毒通过重组出现，M2抑制剂可能是有效的。
Some currently circulating H5N1 strains are fully resistant to these the M2 inhibitors. However, should a new virus emerge through reassortment, the M2 inhibitors might be effective.
此外，流感毒株的类型，品系和致病力以及免疫应答的基本特征，这些都在判定病毒产生耐药的可能性方面起了一定的作用。
In addition, the type, strain, and virulence of the influenza strain and the nature of the immune response all appear to play a role in determining the likelihood of drug resistance arising.
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