目的对口腔缓释粘附片剂与粘附膜剂进行比较。
Objective To compare buccal susutained-release mucoadhesive tablets and mucoadhesive films.
结果以膜剂中大黄酸的释放度为评价指标，膜剂体外缓释效果良好。
RESULTS Using the release rate of Rhein from film as an evaluation index, the in vitro drug releases were well.
结论以壳聚糖接枝甲基丙烯酸甲酯共聚物为成膜材料制备如意金黄散膜剂柔性更好，大黄酸体外缓释效果更明显。
ConclusionRuyijinhuangsan film prepared with Chitosan-graft-poly (Methyl Methacrylate) is more flexible and has better characteristics of sustained-release in vitro than former film.
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