已有研究证实，HIF-1可以上调P-gP，MRP的表达，而且，与P-gp相似，在ABCG2启动子中也存在HIF-1的结合基序(binding motifs)，这强烈提示了HIF-1可能调节ABCG2的表达。
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该单克隆抗体用磷酸化丝氨酸14-3-3结合基序多肽免疫动物制备。
Monoclonal antibody is produced by immunizing animals with phospho-(Ser) 14-3-3 binding motif peptides .
认为脯氨酸等氨基酸的高比例特性以及结合基序特征可以很好地解释羟基磷灰石的生物可利用性和安全性。
The high proportion of proline and other special amino acids in HA binding peptides and motifs was well matched to HA in its bioavailability and safety.
特异的信号基序不仅包括蛋白激酶可以识别的序列(1)，也包括那些能够被磷酸化依赖结合蛋白如14-3-3识别的序列(2)。
Specific signaling motifs include not only sequences that are recognized by protein kinases (1), but also those that are recognized by phosphorylation-dependent binding proteins such as 14-3-3 (2).
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