A TRA对SY5Y细胞有抗增殖作用和诱导细胞分化作用,并呈一定时间和剂量依赖关系。
ATRA could induce morphological differentiation and inhibit growth of SY5Y cells and showed time and dose dependent manner.
目的:探讨蝌蝌提取液(T871)对白血病细胞的诱导分化作用。
Objective: To investigate the induction of differentiation by tadpole extract (T871) on leukemia cells.
结果表明,在适当的用药浓度下,从细胞生长抑制情况、形态学观察及NBT还原能力测定判断,三种药物对HL - 60细胞有明显的诱导分化作用。
It was found that these three compounds can induce the differentiation of HL-60 cells in vitro, judged by cell growth inhibition, morphologic observation and NBT reduction ability.
These signaling proteins play important roles in determining how many cells differentiate down particular pathways and they turn out also to be very useful for treating diseases of those pathways.
这些信号蛋白在决定特定分化路径上,有多少细胞在分化时起着重要作用,且在治疗疾病方面也很有用,同样也是利用这些机制
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