In vitro mediator and/or cytokine release tests have been used in the study of basophil activation. However,these tests are time consuming with low sensitivity and specificity.
现有的方法通过检测细胞介质和细胞因子释放量来观察嗜碱粒细胞活化,操作较困难而且敏感性和特异性也不理想。
参考来源 - 流式细胞术下观察地塞米松和环孢素对嗜碱粒细胞活化的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:检测IL - 12对肥大细胞介质分泌的影响并探讨其可能的信号转导通路。
Abstract: Objective to investigate the effect of IL-12 on mediator release from mast cells and the potential signal transduction pathways correspondingly.
随着时间的推移,它通过消耗神经细胞中一种叫做P物质(或称肽物质,一种神经传递介质)的化学物质来减轻疼痛,该物质使痛觉信号沿神经末梢传递至大脑。
Over time, it short-circuits pain by depleting nerve cells of a chemical called substance p, which helps transfer pain signals along nerve endings to the brain.
嗜碱性粒细胞不是真正的巨噬细胞,但也含有大量的组胺和其他炎症介质。
Basophils are not true phagocytes but contain large amounts of histamine as well as other mediators of inflammation.
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