复方菊冰喷雾剂的毒性试验研究-药学论文-中国论文联盟 关键词】 复方菊冰喷雾剂;急性毒性;局部刺激性;纤毛毒性 [gap=1375]Key words:compound Jubing spray;acute toxicity;local irritation;ciliotoxicity
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粘膜和纤毛毒性 Mucosa And Cilium Toxicity
In the reseach of toxicity of the gel nasal administration, the method of rat nasal cilium toxicity evaluation is chosen, and no apparent nasal mucosa and cilium toxicity was manifested in the test.
鼻腔给药毒性初步研究选用大鼠鼻纤毛毒性评价法,结果表明本品无明显的鼻黏膜和纤毛毒性。
参考来源 - 苍夷滴鼻生物黏附凝胶药学部分研究·2,447,543篇论文数据，部分数据来源于NoteExpress
结论：上述胰岛素鼻喷雾剂无急性鼻粘膜纤毛毒性。
CONCLUSION: This nasal insulin spray has no damage to the nasal mucosas of rats.
本发明制剂具有治疗糖尿病药效确切，使用方便、起效迅速，给药体积小，对鼻纤毛毒性小的优点。
The agent of the invention has the advantages of definite treating effects of diabetes, convenient use, rapid effects, small volume of administration and few side effects to nasal cilia.
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