细胞治疗已有数百年历史。首次细胞治疗概念可以追溯到1493年至1541年,由菲律宾学者Auredus Paracelsus提出。
细胞治疗 Cell therapy ; Cytotherapy ; cellular therapy ; cell therapies
国际细胞治疗协会 ISCT ; International Society for Cellular Therapy
干细胞治疗 stem cell therapy ; nerual stem cells
细胞治疗和再生医学 CTRM
细胞治疗学会 ASGCT
国际细胞治疗学会 ISCT ; International Society of Cell Therapy
美国细胞治疗 Cell Therapeutics
体细胞治疗 Somatic Cell Therapy
又称活细胞治疗 live cell therapy
世界干细胞治疗中心 WSTC
There are many difficulties to solve on the effect and safety of the cell therapy.
然而,在临床前期体内实验方面仍然面临着众多困惑,细胞治疗的安全性和有效性方面存在诸多亟待解决的难点。
参考来源 - 骨髓间充质干细胞治疗食蟹猴脑出血及脑内单次给药的毒性实验研究Bone marrow mesenchymal stem cells (BMSCs) are candidates for such a cell-based therapy, since they display an extensive tropism for gliomas in vitro and in vivo.
因骨髓间充质干细胞(bone marrow mesenchymal stem cells, BMSCs)体内体外均显示很强的胶质瘤趋化性,所以应用BMSCs治疗胶质瘤即是很好的细胞治疗手段。
参考来源 - 骨髓间充质干细胞在成神经分化过程中的定向迁移研究·2,447,543篇论文数据,部分数据来源于NoteExpress
干细胞治疗领域的好消息来自本周发表在《柳叶刀》杂志上的一篇论文。
The good news for the field of stem-cell therapy comes from a paper published in this week's Lancet.
十名病人接受干细胞治疗,四名病人接受安慰剂治疗。
通过标准的行为测试,他们认为干细胞治疗降低了患者的致残率。
Using standard behavioural tests, they concluded that the treated patients had lower disability scores.
Well, I talked about the problem of using plasmids in gene therapy, that it's very difficult to get them into cells.
我们之前讨论过,基因治疗中运用质粒的问题,质粒本身极难进入细胞
This is a way of introducing cytotoxicity or cell killing ability into a cell, and that's been used to treat many kinds of cancers, particularly cancers of the brain.
这种方法常用来导入细胞毒素,或者赋予细胞杀伤其他细胞的能力,以治疗多种癌症,特别是脑癌
These signaling proteins play important roles in determining how many cells differentiate down particular pathways and they turn out also to be very useful for treating diseases of those pathways.
这些信号蛋白在决定特定分化路径上,有多少细胞在分化时起着重要作用,且在治疗疾病方面也很有用,同样也是利用这些机制
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