Hegedus等将几种酪氨酸激酶抑制剂(tyrosine kinase inhibitor,TKI)与肿瘤细胞中分布最广泛、作用最强的多药转 运蛋白MDR1和MRP1直接作用,发现转运并非直接取决于 ...
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一种酪氨酸激酶抑制剂 TKI ; tyrosine kinase inhibitor
结论AG490作为一种酪氨酸激酶抑制剂,能影响正常细胞的功能。
Conclusion As an inhibitor of JAK, AG490 can influence the function of normal cells.
因此,本研究的目的是调查金雀异黄素,一种蛋白质酪氨酸激酶抑制剂,对有急性或慢性糖尿病炎症小鼠(诱导脲佐菌素)的影响。
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
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